19
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10404 | ATP synthase inhibitor 1 | ATPase | |
ATP synthase inhibitor 1 is an inhibitor of the c subunit of the F1/FO-ATP synthase complex. It inhibits mitochondrial permeability transition pore (mPTP) opening and does not affect ATP levels. | |||
T15373 | Gboxin | ATPase , Mitochondrial Metabolism | |
Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity. | |||
T61649 | ATP synthase inhibitor 2 | ||
ATP Synthase Inhibitor 2, a compound targeting Pseudomonas aeruginosa (PA) ATP synthase with an IC50 of 10 μg/mL, fully inhibits the ATP synthesis activity of PA at a concentration of 128 μg/mL [1]. | |||
T1940 | BTB06584 | RAAS , ATPase | |
BTB06584 is an IF1-dependent, selective inhibitor of the mitochondrial F1 Fo-ATPase. BTB06584 is a novel acetohydroxyacid synthase(AHAS) inhibitor, a promising drug target against Mycobacterium tuberculosis (MTB). | |||
T60877 | Mtb ATP synthase-IN-1 | ||
Mtb ATP synthase-IN-1 (compound 6ab) can be used in anti-mycobacterium research. Mtb ATP synthase-IN-1 shoys low cytotoxicity (Vero IC 50 > 64 μg/mL) and acceptable oral bioavailability that has good metabolic stability.... | |||
T79004 | ATP synthase inhibitor 2 TFA | ||
ATP Synthase Inhibitor 2 (Compound 22) TFA is a potent inhibitor of Pseudomonas aeruginosa ATP synthase with an IC50 value of 10 μg/mL. It effectively halts ATP synthesis in Pseudomonas aeruginosa at a concentration of 1... | |||
T6323 | Oligomycin A | MCH 32 | ATPase , Antibiotic , Antifungal |
Oligomycin A (MCH 32) is an inhibitor of ATP synthase, inhibits oxidative phosphorylation and all the ATP-dependent processes occurring on the coupling membrane of mitochondria. | |||
T24111 | GSK3i XIII | GSK3 inhibitor XIII,GSK3iXIII,GSK3i-XIII | GSK-3 |
GSK3i XIII (GSK3 inhibitor XIII) is a GSK-3 ATP-binding site inhibitor. | |||
T6820 | D-α-Hydroxyglutaric acid disodium | D-alpha-Hydroxyglutaric acid disodium salt,Disodium (R)-2-Hydroxyglutarate | ATPase , Others , Reactive Oxygen Species , Endogenous Metabolite , mTOR |
D-α-Hydroxyglutaric acid disodium (Disodium (R)-2-Hydroxyglutarate) is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM. | |||
T21023 | Bedaquiline fumarate | TMC 207,R403323,TMC-207,TMC207,R-403323,R 403323 | Antibacterial , Antibiotic |
Bedaquiline fumarate (TMC207), a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections. It blocks the proton pump for ATP synthase of mycobacteria. ... | |||
T3067 | Tideglusib | NP-12,NP031112 | GSK-3 |
Tideglusib (NP031112), a non-ATP competitive inhibitor of glycogen synthase kinase 3 (GSK-3), is with anti-inflammatory and neuroprotective activities. | |||
T36624L | α-Hydroxyglutaric Acid Lithium | α-Hydroxyglutaric Acid Lithium(2889-31-8 Free base) | Decarboxylase , Endogenous Metabolite , mTOR |
α-Hydroxyglutaric Acid Lithium, converted from glutamate in microorganisms and animals, is an inhibitor of α-ketoglutarate-dependent dioxygenase and 5-methylcytosine hydroxylase, and has an inhibitory effect on ATP synth... | |||
T14066 | 9-ING-41 | Apoptosis , GSK-3 , Autophagy | |
9-ING-41 is a glycogen synthase kinase-3 inhibitor. | |||
T4861 | Trans-Aconitic acid | ATPase , Endogenous Metabolite | |
Trans-Aconitic acid is normally present in normal human urine, and it has been suggested that is present in larger amounts with Reye's syndrome and organic aciduria. trans-Aconitic acid is a substrate of enzyme trans-aco... | |||
T26843 | BMS-199264 hydrochloride | ||
BMS-199264 hydrochloride potently inhibits the ATP hydrolase activity of mitochondrial F1F0 ATP synthase. | |||
T12298 | Oligomycin B | Others | |
Oligomycin B is an antibiotic isolated from marine Streptomyces, is an eukaryotic ATP synthase inhibitor, induces apoptosis. | |||
T38231 | Isoapoptolidin | ||
Isoapoptolidin is a stable derivative of apoptolidin that demonstrates 10-fold reduced F1FO-ATP synthase inhibitory activity compared to apoptolidin (IC50s = 17 and 0.7 μM, respectively). | |||
T74033 | 6-Me-ATP | ||
6-Me-ATP (N6-Methyl-ATP), a N6-modified adenosine triphosphate (ATP) derivative, exhibits strong binding affinity for glycogen synthase kinase 3 (GSK3) and acts as the phosphate group donor in GSK3β-catalyzed phosphoryla... | |||
T35560 | SAR502250 | ||
SAR502250 is a potent, selective, ATP-competitive, orally active, and brain-penetrant GSK3 inhibitor with a human GSK-3β IC50 value of 12 nM. It exhibits antidepressant-like activity and is being researched for potential... |